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Local Anesthetic Pain Killer Procaine Novocaine Raw Powder For Pain Relif Cas 59-46-1

Categories Local Anesthesia Drugs
Brand Name: Pain Killers
Model Number: Local Anesthesia Powder
Certification: GMP; ISO; SGS
Place of Origin: China
MOQ: 10 g
Price: USD1/10g~USD100/10g
Payment Terms: Western Union, T/T, Money Gram, Paypal
Supply Ability: 1000kg/mouth
Delivery Time: Within 24hours after received your payment
Packaging Details: vial and foil bag
Product name: Procaine
Other name: 2-(Diethylamino)ethyl 4-aminobenzoate
Number: 59-46-1
M.F.: C13h20n2o2
M.W.: 236.31
Packaging: foil bag or vial
Appearance: White Crystalline Powder
Assays: 99%
Shipping: by express (FedEx,UPS,DHL,EMS), by air and by sea
Payment: estern Union, Money Gram, T/T and Paypal
WhatsApp: +8618873306038
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    Local Anesthetic Pain Killer Procaine Novocaine Raw Powder For Pain Relif Cas 59-46-1

    Local Anesthetic Pain Killer Procaine ( Novocaine ) Raw Powder For Pain Relif Cas 59-46-1

    What is procaine?

    Procaine is a local anesthetic. Procaine causes loss of feeling (numbness) of skin and mucous membranes.

    Procaine is used as an injection during surgery and other medical and dental procedures.

    Procaine may also be used for purposes other than those listed here.


    Product Details

    Procaine is a local anesthetic drug of the amino ester group. It is used primarily to reduce the pain of intramuscular injection of penicillin, and it is also used in dentistry. Owing to the ubiquity of the trade name Novocain, in some regions, procaine is referred to generically as novocaine. It acts mainly as a sodium channel blocker.Today it is used therapeutically in some countries due to its sympatholytic, anti-inflammatory, perfusion-enhancing, and mood-enhancing effects.


    Product Name:PROCAINE
    Synonyms:2-(Diethylamino)ethyl 4-aminobenzoate;2-(Diethylamino)ethyl p-aminobenzoate;2-(diethylamino)ethylp-aminobenzoate;2-diethylaminoethyl4-aminobenzoate;2-Diethylaminoethylester kyseliny p-aminobenzoove;2-diethylaminoethylesterkyselinyp-aminobenzoove;2-diethylaminoethylp-aminobenzoate;4-Aminobenzoic acid diethylaminoethyl ester
    CAS:59-46-1
    MF:C13H20N2O2
    MW:236.31
    EINECS:200-426-9
    Product Categories:
    Mol File:59-46-1.mol
    PROCAINE Structure

    PROCAINE Chemical Properties
    Melting point61°
    Boiling point378.78°C (rough estimate)
    density1.0604 (rough estimate)
    refractive index1.5430 (estimate)
    pkapKa 9.04±0.01(H2O,t=25,I=0.1(NaCl))(Approximate)
    Merck14,7757

    PROCAINE Usage And Synthesis
    Usesinhibitor of sodium channel
    DefinitionChEBI: A benzoate ester, formally the result of esterification of 4-aminobenzoic acid with 2-diethylaminoethanol but formed experimentally by reaction of ethyl 4-aminobenzoate with 2-diethylaminoethanol.
    Contact allergensProcaine is a local anesthetic with para-amino function. Sensitization mainly concerns the medical, dental, and veterinary professions.


    Indication


    Used as a local anesthetic primarily in oral surgery


    Pharmacodynamics


    Procaine is an anesthetic agent indicated for production of local or regional anesthesia, particularly for oral surgery. Procaine (like cocaine) has the advantage of constricting blood vessels which reduces bleeding, unlike other local anesthetics like lidocaine. Procaine is an ester anesthetic. It is metabolized in the plasma by the enzyme pseudocholinesterase through hydrolysis into para-aminobenzoic acid (PABA), which is then excreted by the kidneys into the urine.


    Mechanism of action


    Procaine acts mainly by inhibiting sodium influx through voltage gated sodium channels in the neuronal cell membrane of peripheral nerves. When the influx of sodium is interrupted, an action potential cannot arise and signal conduction is thus inhibited. The receptor site is thought to be located at the cytoplasmic (inner) portion of the sodium channel. Procaine has also been shown to bind or antagonize the function of N-methyl-D-aspartate (NMDA) receptors as well as nicotinic acetylcholine receptors and the serotonin receptor-ion channel complex.



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    MOQ:100ml

    Package:Disguised & Discreet pkg
    Payment:T/T,Western Union,Moneygram,bitcoin
    Delivery: sent out the goods within 24hours after receiving payment.
    Custom Pass rate:99%
    Resend policy is available if the parcle is seized or any quality problems been found.

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    Local Anesthesia

    BenzocainePrilocainePropitocaine hydrochloride
    BupivacaineTetracaineProparacaine hydrochloride
    LidocaineTetracaine hydrochlorideBupivacaine hydrochloride
    Linocaine hydrochloridePramoxine hydrochlorideDibucaine hydrochloride
    ProcaineArticaine hydrochlorideRopivacaine hydrochloride
    Procaine hydrochlorideBenzocaine hydrochlorideLevobupivacaine Hcl

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